GDT Polydioxanone PLX Suture

Overview of GDT PLX Sutures

GDT PLX Sutures are sterile, synthetic, absorbable monofilament sutures composed of Polydioxanone, a polymer known for being non-antigenic, non-pyrogenic, and eliciting only a slight tissue reaction during absorption. Dyed with D&C Violet No. 2 during polymerization, these sutures provide excellent visibility. The sutures are permanently attached to 3/8 Circle 20.0mm Reverse Cutting hardened stainless steel needles, ensuring durability and precision during surgical procedures.

Product Specifications

Our GDT Surgical Polydioxanone (PLX) Sutures are composed of a synthetic homopolymer of polyester, poly (p-dioxanone). They retain 70% of their initial tensile strength after 2 weeks, 50% after 4 weeks, and 25% after 6 weeks, providing the longest period of wound support among absorbable sutures. Complete absorption occurs within 180 days. These sutures are available in USP sizes 3-0, 4-0, and 5-0, each with a length of 75.0 cm.

Features and Benefits

• Great Knot Security: Ensures reliable and secure wound closure.
• Easy Knot Placement: Facilitates efficient and effective surgical procedures.
• Smooth Passage Through Tissues: The monofilament structure allows for easy and atraumatic tissue passage.
• Minimal Tissue Reactivity: One of the safest materials for implantation, causing negligible tissue reaction.
• Unique Tensile Strength: Provides extended wound support, making it ideal for soft tissue management and Guided Tissue Regeneration (GTR).
• Excellent Histocompatibility: Ensures biocompatibility and patient safety.
• Predictable Absorption Rate: Gradual loss of tensile strength and mass, absorbed by hydrolysis.

Indications and Selection

GDT PLX Sutures are indicated for use in all types of soft tissue approximation, including pediatric cardiovascular tissue where growth is expected, ophthalmic, and dental surgery. They are particularly beneficial when an absorbable suture with extended wound support (up to six weeks) is required. The selection of sutures should be based on the patient's condition, surgical experience, technique, and wound size.

Performance and Benefits

GDT PLX Sutures lead to the ingrowth of fibrous connective tissue due to minimal initial inflammatory reaction. The sutures gradually lose tensile strength and are absorbed by hydrolysis, with the co-polymer degrading into monomeric acid, specifically 2 hydroxyethoxyacetic acid, which is subsequently absorbed and eliminated by the body. The performance of these sutures in terms of tensile strength is as follows:

• Approximately 78.45% at 14 days
• Approximately 69.7% at 28 days
• Approximately 57.95% at 43 days
• Approximately 40.55% at 57 days

These sutures exhibit excellent elasticity, very low tissue reaction, and smooth passage through tissues due to their low frictional coefficient. They provide superior wound support with minimal complications, ensuring effective and reliable surgical outcomes.