NovaBone® Dental Putty in Syringe
Osteogenics · source
Unique Formulation
NovaBone® Dental Putty is 100% synthetic and fully resorbable. It is composed of calcium phosphosilicate (CPS) particles in a bimodal size distribution combined with a polyethylene glycol and glycerine binder. The binder improves handling and aids in maintaining the space between the particles, which facilitates revascularization after implantation. The bioactive CPS component makes up 70% of the putty by volume. Upon implantation, the water soluble binder is absorbed within 24 to 72 hours, creating a 3-dimensional porous scaffold that facilitates diffusion of blood and tissue fluids through the matrix. The smaller CPS particles (32-125 μm) are more rapidly resorbed, providing the initial burst of Ca and P ions. Subsequently, the larger particles (90-710 μm) react, and being more resistant to resorption, continue the process of bone regeneration.
Osteostimulative & Osteoconductive
Unlike most synthetic grafts that are only osteoconductive, bioactive NovaBone® Dental Putty also has an "osteostimulative" effect. After implantation, surface reactions result in absorption of the graft material, a controlled release of Si, Ca, and P ions, and concurrent new bone formation. These surface reactions result in an osteostimulative affect, defined as the stimulation of osteoblast proliferation in vitro as evidenced by increased DNA content and elevated osteocalcin and alkaline phosphatase levels. In vitro gene array analysis has confirmed that when human primary osteoblasts are exposed to extracts of CPS, upregulation of several gene families occurs.
Handling
NovaBone® Dental Putty significantly simplifies bone graft handling and delivery. It is ready to use and extremely user friendly. It is pre-mixed, cohesive, moldable, and adaptable. NovaBone® Dental Putty is stable at room temperature, does not require refrigeration, has a 4-year shelf-life, and appears radiodense on radiographs.
Key Features
- Uni-dose syringe delivery method allows clinician to clearly see how much bone graft is being used
- 100% synthetic and resorbable Calcium Phosphosilicate dental putty
- Osteostimulatory effect of material results in stimulation of osteoblast proliferation
- More than 20 years of international clinical use and more than 50 studies on file
Informations produit
| Fabricant | Osteogenics |
|---|---|
| Storage | Room temperature, does not require refrigeration |
| Shelf Life | 4-year |
| Composition | 100% synthetic and fully resorbable calcium phosphosilicate (CPS) particles in bimodal size distribution with polyethylene glycol and glycerine binder |
| Radio-opacité | Radioopaque sur les radiographies |
| Clinical History | More than 20 years of international clinical use with more than 50 studies on file |
| Binder Absorption Time | 24 to 72 hours |
| Available Syringe Sizes | 0.5 CC, 1.0 CC, 2.0 CC |
| Bioactive Cps Component | 70% of the putty by volume |
| Larger Cps Particles Size | 90-710 μm |
| Smaller Cps Particles Size | 32-125 μm |
